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KMID : 1038620210390010072
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Radiation Oncology Journal
2021 Volume.39 No. 1 p.72 ~ p.77
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Clinical behaviour and outcome in pediatric glioblastoma: current scenario
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Singla Aditya Kumar
Madan Renu
Gupta Kirti
Goyal Shikha
Kumar Narendra
Sahoo Sushant Kumar
Uppal Deepak K.
Ahuja Chirag K.
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Abstract
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Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018?2019.
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KEYWORD
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Child, Glioblastoma, Genetics, Radiotherapy, Temozolomide
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